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N,N-Dimethyltryptamine OR DMT is a chemical substance that occurs in many plants and animals and which is both a derivative and a structural analog of tryptamine. It can be consumed as a psychedelic drug and has historically been prepared by various cultures for ritual purposes as an entheogen. Dimethyltryptamine is illegal in most countries.
Dimethyltryptamine has a rapid onset, intense effects, and a relatively short duration of action. For those reasons, Dimethyltryptamine was known as the “business trip” during the 1960s in the United States, as a user could access the full depth of a psychedelic experience in considerably less time than with other substances such as LSD or magic mushrooms.
Dimethyltryptamine is a functional analog and structural analog of other psychedelic tryptamines such as O-Acetylpsilocin (4-AcO-DMT), 5-MeO-DMT, bufotenin (5-HO-DMT), psilocybin (4-PO-DMT), and psilocin (4-HO-DMT). The structure of Dimethyltryptamine occurs within some important biomolecules like serotonin and melatonin, making them structural analogs of Dimethyltryptamine .
DMT’s Short-Term Effects
DMT is commonly taken by users seeking a psychedelic “trip” similar to those produced by the ingestion of LSD or psilocybin. Many drug users choose DMT as an alternative to LSD because the duration of the trip is much shorter, lasting approximately 30 to 45 minutes rather than several hours, as is the case with LSD.
The drug has a rapid onset and effects are typically felt immediately.
A hallucinogenic Dimethyltryptamine trip usually results in
- Altered perception of time and space.
- Feelings of intense joy.
- Visual and auditory hallucinations.
- Out-of-body experience.
- Perception ofbright, intensified colors.
- Perceived insights or epiphanies (often believed to have come from aliens, divinities or other mystical beings).
Physiological side effects of Dimethyltryptamine may include 1,2:
- Dilated pupils.
- Involuntary rapid eye movement.
- Increased heart rate.
- High blood pressure.
- Coordination problems.
- Nausea and vomiting (typically when taken in oral forms such as ayahuasca).
- Coma and/or respiratory arrest (reported in high doses).